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Botanist-turned-teacher Liam Garvey describes his ultimate reward as "when a kid gets it. You see the light of understanding; that's the kick."

As a prestigious Princeton fellowship came to an end, Ethan Perlstein decided to strike out on his own.

"You can get encouragement to hostility depending on what we are saying and who we are talking to," says Helen Wallace. A firm belief in the issues you are campaigning for and the ability to stand your ground are vital skills for lobbyists.

"I enjoy ... making a difference and seeing how much the world of antidoping has developed in the last few years." --Osquel Barroso

The best and most popular stories of 2012, as chosen by readers and editors.

In science, sometimes, mistakes are not merely good, they're extraordinary.