"Cases very soon demonstrated a great capacity for working with software and developing systems, a capacity that is unfortunately quite exceptional in experimental biologists." --Systems biologist Alfonso Valencia.
The most uplifting moments for me are those when a biological question generates new mathematically interesting theories and results and when these results give new insights into the original biological problem.
I knew a little molecular biology, but I had no notion of what you could do experimentally. It reminded me of electronics, the idea that you had these tools to splice things together in an ordered way, that you could reengineer things in the cell to do something else. --Mark Goulian