Issues & Perspectives

As the Sangji case moves towards a legal judgment, will the academy learn its lessons?

A new NIH center aims to set the national agenda on translational research, but budget constraints mean not much change for now.

A Spanish molecular nanotechnology researcher, TR35 Innovator of the Year, company founder, and policy adviser encourages early-career scientists to incite scientific revolutions.

A good mentor at each career stage can greatly enhance your professional and personal achievement.

Here's what academic scientists need to know about the biggest change to U.S. patent law in 60 years.

Lab work left you feeling dissatisfied? Our Experimental Error columnist feels your pain.

A more relaxed, decisive, and authoritative voice can be a definite asset in a scientific career.

Paula Stephan's new book looks beyond rosy press releases to uncover the harsh economic realities of the academic job market.

The best and most popular stories of 2011, as chosen by readers and editors

Kimberly Powers's epidemiological research on HIV helped set the stage for this year's Science Breakthrough of the Year.

Looking for something really different? Consider a career in alchemy, Lysenkoism, diluvial geology -- or invent your own!

A study confirms that girls have as much innate math ability as boys -- so where are all the women mathematicians?

We present our best information and advice on working in the pharmaceuticals industry.

Scientists seeking pharma careers must adapt to sweeping changes in the industry.

Graduate students need to decide whether to spend time replicating other scientists' data.