Articles in this series come to you through a collaboration between Next Wave and Science's aging knowledge environment, SAGE KE. The joint venture, which is supported by the AARP Andrus Foundation, is intended to profile the careers of individuals working to further our understanding of the biology of aging.

The Scientists and the Issues Surrounding the Science of Aging

Discover the people behind the papers and the career issues they confront by reading their essays and profiles.

  • A Life of Fusion Olivia Pereira-Smith moved from Bombay to Berkeley to pursue science. Focusing initially on experiments that merged cells, she built a career in gerontology and a successful working relationship with her husband and research partner.

  • Wind at His Back Grad student Trey Powers has hunted with hawks and raced yachts. Now he's navigating his way toward an understanding of how yeast cells age.

  • Tying It Together Rudi Westendorp is one of those rare individuals whose work unites geriatrics, clinical epidemiology, and the biology of aging.

  • Eyes Wide Open    Science academics who take the path into commerce may find rude surprises awaiting ? an insider's guide to the pros and cons of getting involved with the biotech industry.

  • Focusing on the Big Picture    Adam Gazzaley, neurobiologist and photographer, began his studies of cognitive aging with a microscope. Now he's peering through the wide-angle lens of whole-brain imaging.

  • The Mouse that Roared    Andrzej Bartke began studying reproductive hormones in dwarf mice as a grad student. Thirty years later, his lab serendipitously discovered that the midget mice are long-lived.

  • Funded Up and Raring to Go    The nonprofit American Federation for Aging Research has just announced its 2003 grant awardees, and four winners tell how they plan to use the money.

  • Chasing 100    Ten years ago, geriatrician Thomas Perls couldn't understand why his 100-year-old patients were never in their rooms. He started looking into why, and he hasn't stopped since.

  • Science on the Fly    In pursuit of his research objectives, Marc Tatar has chased butterflies, dodged rattlesnakes, and chomped on termites. Now he's leading the pack in efforts to decipher how hormones control aging in fruit flies.

  • Renaissance Woman    Geneticist, artist, and bon vivant Nadia Rosenthal (pictured left) moved to Italy to make a go of the European Molecular Biology Laboratory's mouse biology program.

  • Great Expectations    Florian Muller was 12 when he first imagined that genetic engineering might someday extend life span. A dozen years later, he's still pursuing that vision: As a first-year grad student, he is investigating whether interventions that reduce oxidative damage could stretch longevity or ameliorate age-related diseases.

  • The Networker    Molecular biologist Brian Clark works tirelessly to discover and develop connections among Europe's biogerontologists.

  • The Accidental Biologist    Geneticist Eugenia Wang crossed the Pacific from Taiwan to forge a life for herself in the world of science.

  • All That Jazz    After playing saxophone in Tel Aviv, Amsterdam, and Boston, Adam Antebi has stepped up to his most challenging gig yet: deciphering the links between endocrinology and longevity in the nematode.

  • Mindful of Metal    Footballer, neuroscientist, and former stand-up comic, Ashley Bush keeps hammering at the idea that a glut of metals in elderly brains galvanizes Alzheimer's disease.

  • Shooting for the Stars    Been there, done that. Biochemist-in-training Bridget Williams tells other students the good, the bad, and the ugly about getting a Ph.D. in science.

  • Wake-Up Call    A software engineer is the last person you'd expect to see dissecting the biology of aging. But Aubrey de Grey's radical views have stirred up debate in the field of gerontology.

  • Listening to the Song of Senescence    Caleb Finch, a biogerontologist and bluegrass fiddler, has woven diverse themes into a research opus on aging.

  • Endless Drive    Vicki Lundblad won first prize at the science fair in seventh grade. Today, she's unraveling the mechanisms that cells use to protect the ends of their chromosomes.

  • Hungry for Science    Edward Masoro began studying calorie restriction and life-span in 1975, when he was 51. Now 78, his appetite for gerontology is far from sated.

  • Rookie Rising    Matt Kaeberlein fermented a breakthrough in the genetics of yeast aging. His next feat: starting a biotech firm.

  • Ageless Activist    Irrepressible Paola Timiras survived World War II to champion education on aging. She's still going strong.

  • Head Rush    William Sonntag's early interest in psychology launched his studies of how growth hormone influences aging of the brain.

  • The Drifter    Gary Ruvkun's career has meandered from planting trees to studying aging in worms. Next on his horizon: hunting for life on Mars.

A complete list of the articles in their SAGE KE manifestations is also available on the SAGE KE Trainee Resources page.