This article was originally published on 7 April 2010.
The podcast features an interview with Garret FitzGerald , director of the Institute for Translational Medicine and Therapeutics  at the University of Pennsylvania School of Medicine in Philadelphia. FitzGerald and colleague Carsten Skarke  write in a Perspective , published this week in Science Translational Medicine, that expertise in translational medicine and therapeutics is scarce in academia, industry, and regulatory bodies.
"To facilitate the translation of more personalized therapeutics, we require investigators facile with model systems, informatics, principles of drug action, quantitative signatures of drug exposure, and both mechanism-based and unbiased readouts of drug effects," they write. The article goes on to describe how such expertise could be developed.
In the podcast interview , FitzGerald further discusses translational medicine and therapeutics as a specific subset of clinical and translational science, where deficits exit in the workforce, and how researchers can direct their training to prepare themselves for a career in translational science.
Find more online:
-Podcast Transcript 
-Perspective: "Training Translators for Smart Drug Discovery ," Science Translational Medicine, 7 April 2010.